Faculty Information

Dong H. Kim, M.D.

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AWARDS:

• Valedictorian, Glen A. Wilson High School, 1982
• Regents Scholar, University of California, 1982
• Alumni Scholar, University of California, 1982
• Graduation with Honors, Stanford University, 1986
• Meritorious Research, Western Student Medical Research Forum, 1988
• Henry Newman Award, San Francisco Neurological Society, 1993
• Bayer Cerebrovascular Award, 1999

PATENTS:

• "Genetic gains and losses in gliomas." U.S. Patent Office Serial # 08/403,457a

COMMITTEES:

• UCSF Representative, Western Student Medical Research Committee, 1988-1990
• Sargeant at Arms Committee, Congress of Neurological Surgeons, 1995
• Research Committee, University of Texas 1999 - 2001
• Scientific Review Committee, Congress of Neurological Surgeons, 2001 -

SELECTED PUBLICATIONS:

2. Kim DH, Barbaro NM, Fields HL: Hyperalgesia following naloxone precipitated withdrawal from morphine. Clin Res 36, No. 1, 1988

3. Kim DH, Bederson JB, Fields HL, Barbaro NM: Hyperalgesia occurs with acute withdrawal from spinal or periaqueductal grey administered morphine. Clin Res 37, No. 1, 1989

4. Kim DH, Fields HL, Barbaro NM: Morphine analgesia and acute physical dependence: rapid onset of two opposing, dose-related processes. Brain Research 516, 1990.

5. Kim DH, Harsh GR IV: Advances in brain tumor biology, the genetics of astrocytoma. Curr Techniques in Neurosurgery, 1993.

6. Kim DH, Maeda T, Mohapatra G, Park S, Waldman FW, Gray JW, Feuerstein BG: Molecular cytogenetics of malignant gliomas. J Neuro-Oncology 15, Supp, 1993.

7. Kim DH, Mohapatra G, Bollen A, Waldman FM, Feuerstein BG: Chromosomal abnormalities in glioblastoma multiforme and glioma cell lines detected by comparative genomic hybridization. Int J Cancer 60, 1995.

8. Mohapatra G, Kim DH, Feuerstein BG: Detection of multiple gain and losses in ten glioma cell lines by comparative genomic hybridization. Genes, Chrom, Cancer 13, 1995.

9. Kim DH, Gutin P, Noble LJ, Nathan D, Ross G, Yu JS, Nockels RN. Genetically engineered fibroblasts secreting nerve growth factor or brain-derived growth accelerates recovery from acute, traumatic spinal cord injury in the rat. Neuroreport 7, 1996.

10. Mohapatra G, Moore DH, Kim DH, Grewal L, Hyun WC, Waldman F, Pinkel D, Feuerstein BG: Analyses of brain tumor cell lines confirm a simple model of relationships among fluorescence in situ hybridization, DNA index, and comparative genomic hybridization. Genes, Chrom, Cancer 20, 1997.

11. Mautes AEM, Kim DH, Sharp FR, Panter S, Sato M, Maida N, Bergeron M, Guenther K, Noble LJ: Induction of heme-oxygenase-1 (HO-1) in the contused spinal cord of the rat. Brain Research 795, 1998.

12. Kim DH, Mohapatra G, Feuerstein BG: Genetic tumor markers in gliomas, In: Berger M, Wilson CB, eds. Textbook of Gliomas, 1998.

13. Kim DH, MacDonald J, Day AL: Approaches to terminal basilar bifurcation aneurysms, In: Kaye A, Black P, eds. Operative Neurosurgery, 1999.

14. Nates J, Aristizabal J, Kim DH, Fife C: Venous air embolism during supine craniotomy for aneurysm: role of hyperbaric oxygen therapy. The Internet J Anesthesiology, Vol 4N3, 2000.

15. Morgenstern LB, Demchuk AM, Kim DH, Frankowski RF, Grotta JC. Rebleeding leads to poor outcome in ultra early craniotomy for intracerebral hemorrhage. Neurology, in press.

16. Kim DH, Van Ginhoven G, Milewicz DM: The incidence of familial intracranial aneurysms in 200 patients: comparison between Caucasian, African-American, and Hispanic populations. Neurosurgery 2003, in press.

17. Kim DH, Mathew J, Ziadi S, Nates J, Dannenbaum M, and Malkoff M: Increased cardiac output or mean arterial pressure, but not hypovolemia, can reverse the decrease in CBF from vasospasm following subarachnoid hemorrhage. In press, 2003

18. Kim DH, Tu C, Cassacia-Bonnefil P, Chao M: The neurotrophins prevent apoptotic but not necrotic cell death following neuronal injury by signaling through the trk receptor. In press, 2003.

19. Kim DH, Haney C, and Van Ginhoven G: Measures of outcome following surgical clipping of cerebral aneurysms: an analysis of 500 cases. Submitted, 2003.

20. Kim DH, Zhao X: Caspase activation following neuronal injury and its modulation by the neurotrophins. Submitted 2003.

21. Kim DH: Reductions in medical complications during vasospasm treatment: a focus on cardiac output instead of hypervolemia and induced hypertension. Submitted, 2003.

SELECTED PRESENTATIONS:

American Federation for Clinical Research, Carmel, CA February 1988
"Hyperalgesia following naloxone precipitated withdrawal from morphine."

Society for Neuroscience Annual Meeting, Toronto, Canada November 1988
" Dose response relationship for hyperalgesia following naloxone precipitated withdrawal from morphine."

American Federation for Clinical Research, Carmel CA February 1989
"Morphine analgesia and acute physical dependence."

Tenth International Conference of Brain Tumor Research and Therapy, Voss, Norway September 1993
"Molecular cytogenetics of gliomas using comparative genomic hybridization."

American Association of Neurological Surgeons, San Francisco, CA April 1994
Scientific Session: "Molecular cytogenetics of human gliomas."

American Association of Neurological Surgeons, Minneapolis, MN April 1996
Plenary Session: "Treatment with genetically-engineered fibroblasts secreting nerve growth factor or brain-derived growth factor accelerates recovery from spinal cord injury."

Joint Section on Cerebrovascular Disease, AANS and CNS, Anaheim, CA February 1997
"Basilar apex aneurysms: results from a modern surgical series."

Society for Ambulatory Anesthesia, Orlando, FL May 1997
"Brain Attack."

Southern Neurosurgical Society, Pinehurst, NC June 1997
"The treatment of basilar apex aneurysms."

First Annual Symposium on Neurosurgical Emergencies, The University of Texas Medical School, Houston, TX March 1998
"The management of vasospasm and subarachnoid hemorrhage."

Congress of Neurological Surgeons, Seattle, WA October 1998
"The management of arteriovenous malformations" (luncheon seminar).

Joint Section on Cerebrovascular Disease, AANS and CNS, Nashville, TN, February 1999
"Neurotrophins provide protection from neural injury by signalling through the trk receptors."

Second Annual Symposium on Neurosurgical Emergencies, The University of Texas Medical School, Houston, TX , April 1999
"Emergent assessment and intervention for subarachnoid hemorrhage."

The Third Annual Frontiers in Interventional Cardiology, The University of Texas Medical School, Houston, TX, April 1999
"Carotid and vertebral stenting."

The Society for Neuroscience, Miami, FL, October 1999
"Neurotrophins can protect cortical neurons from hypoxic and irradiation injury by activating the trk receptors and inhibiting caspase-3."

Texas Association of Neurological Surgeons, San Antonio, TX, May 2000
"Multi-modality treatment of intracranial aneurysms."

Texas Association of Neurological Surgeons, San Antonio, TX, May 2002
"The treatment of intracranial aneurysms in 2002: surgical clipping versus endovascular coiling."

Houston Neurological Society, Houston, TX, July 2002
"Cerebral aneurysms."

Books

1. Bailes JE, Day AL (eds.): Neurological Sports Medicine: A Guide for Physicians and Athletic Trainers, AANS Publications, 2001.

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